Costs and Benefits of Branded Drugs: Insights from Cost-Effectiveness Research
نویسندگان
چکیده
Abstract The relationship between costs and health benefits of branded pharmaceuticals remains controversial. This paper examines the incremental incurred for gained from largest available sample cost-effectiveness studies drugs in USA, 1994–2015 Tufts Registry Cost-Effectiveness Analyses. Earlier used small, specialized samples drugs. We use linear regression analysis to estimate association those additional quality-adjusted life years (QALYs) pharmaceutical costs. preferred uses 476 involving with both higher increased effectiveness compared previous standard care. Regressions on QALYs imply that an QALY is associated, average, a $28,561 increase cost (95 % CI, $18,853–$38,270). explains 20 variation In this analytical sample, share is, therefore, not random but rather associated QALYs; prices are some extent “value-based.” Our results robust varying inclusion criteria funding source. subgroup analyses, highest per was $44,367 $35,373–$53,361). Costs data set are, lower than common estimates monetary value American consumers. As other studies, we find sellers patent-protected beneficial new technology appear capture only fraction provided.
منابع مشابه
The Costs, Benefits, and Cost-Effectiveness of Interventions to Reduce Maternal Morbidity and Mortality in Mexico
BACKGROUND In Mexico, the lifetime risk of dying from maternal causes is 1 in 370 compared to 1 in 2,500 in the U.S. Although national efforts have been made to improve maternal services in the last decade, it is unclear if Millennium Development Goal 5--to reduce maternal mortality by three-quarters by 2015--will be met. METHODOLOGY/PRINCIPAL FINDINGS We developed an empirically calibrated m...
متن کاملCosts and Cost Effectiveness of Additive Manufacturing
............................................................................................................................................... II PREFACE ................................................................................................................................................. IV ACKNOWLEDGEMENTS ...............................................................................
متن کاملCost-Effectiveness Analysis Implications for the Measurement of Benefits and Costs of Medical Interventions
متن کامل
The cost-effectiveness, health benefits, and financial costs of new antiviral treatments for hepatitis C virus.
BACKGROUND New hepatitis C virus (HCV) treatments deliver higher cure rates with fewer contraindications, increasing demand for treatment and healthcare costs. The cost-effectiveness of new treatments is unknown. METHODS We conducted a microsimulation of guideline testing followed by alternative treatment regimens for HCV among the US population aged 20 and older to estimate cases identified,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Benefit-cost Analysis
سال: 2022
ISSN: ['2194-5888', '2152-2812']
DOI: https://doi.org/10.1017/bca.2022.12